Background: Oral cancer is one of the highly aggravated conditions of oral pathologies.The commonly diagnosed form of oral cancer is oral squamous cell carcinoma (OSCC).The molecular players responsible for low post-treatment cancer-free survival rate and higher recurrence & metastasis rates associated with OSCC are still obscure.This study aim
Gastroesophageal adenocarcinomas (GEAs) harbor recurrent amplification of KRAS, leading to marked overexpression of WT KRAS protein.We previously demonstrated that SHP2 phosphatase, which acts to promote KRAS and downstream MAPK pathway activation, is a target in these tumors when combined with MEK inhibition.We hypothesized that SHP2 inhibitors ma
Public policies on care services designed by the US government read more are not exempt from certain ideological dimension, which contextualizes the system of providing those services.Taking as starting point a critical review of the concepts of spatial justice and social segregation, a geostatistical methodology multilevel is designed to study the
Erysipelas is one of the first places on the prevalence of infectious disease after acute respiratory and intestinal infections, viral hepatitis.Currently, in most cases erysipelas is caused by beta-hemolytic group A Streptococcus bacterium, but in some cases could be due to co-infection with Staphylococcus aureus.The pathogenesis of erysipelas is
Biological control of plant disease using antagonistic microorganism has been obtaining much attention and implemented for read more decades.One of the potential microorganisms used in this strategy is chitinolytic bacteria.Utilization of this bacteria ranges from cell life, enzymes, genes, or other metabolites.In this study, we examined the abilit